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Product Name OTOS Chinese Name 耳蜗蛋白OTOS抗体 Alias Organ of Corti 10 kDa protein; OTOS; OTOSP; OTOSP_HUMAN; Otospiralin. Research Area Cell biology Developmental biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 8kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OTOS: 22-89/89 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Otospiralin is synthesized by nonsensory cells (fibrocytes) of the inner ear, and downregulation of otospiralin in guinea pigs leads to deafness (Lavigne-Rebillard et al., 2003 [PubMed 12687421]).[supplied by OMIM, Mar 2008]
Function:
May be essential for the survival of the neurosensory epithelium of the inner ear.
Subcellular Location:
Secreted.
Tissue Specificity:
Ear specific.
Similarity:
Belongs to the otospiralin family.
SWISS:
Q8NHW6
Gene ID:
150677
Database links:Entrez Gene: 150677 Human
Entrez Gene: 260301 Mouse
Omim: 607877 Human
SwissProt: Q8NHW6 Human
SwissProt: Q8R448 Mouse
Unigene: 148586 Human
Unigene: 219545 Mouse
Unigene: 56698 Rat
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