Product Name	OTOS
Chinese Name	耳蜗蛋白OTOS抗体
Alias	Organ of Corti 10 kDa protein; OTOS; OTOSP; OTOSP_HUMAN; Otospiralin.
Research Area	Cell biology  Developmental biology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	8kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human OTOS: 22-89/89
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Otospiralin is synthesized by nonsensory cells (fibrocytes) of the inner ear, and downregulation of otospiralin in guinea pigs leads to deafness (Lavigne-Rebillard et al., 2003 [PubMed 12687421]).[supplied by OMIM, Mar 2008] Function: May be essential for the survival of the neurosensory epithelium of the inner ear. Subcellular Location: Secreted. Tissue Specificity: Ear specific. Similarity: Belongs to the otospiralin family. SWISS: Q8NHW6 Gene ID: 150677 Database links: Entrez Gene: 150677 Human Entrez Gene: 260301 Mouse Entrez Gene: 246044 Rat Omim: 607877 Human SwissProt: Q8NHW6 Human SwissProt: Q8R448 Mouse SwissProt: Q8K560 Rat Unigene: 148586 Human Unigene: 219545 Mouse Unigene: 56698 Rat

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