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Product Name OSTF1 Chinese Name 破骨细胞刺激因子1抗体 Alias bA235O14.1; FLJ20559; OSF; Osteoclast stimulating factor 1; Osteoclast-stimulating factor 1; Ostf1; OSTF1_HUMAN; SH3P2. Research Area Cell biology Developmental biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 24kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OSTF1: 101-200/214 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).[supplied by OMIM, Mar 2008]
Function:
Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Ubiquitously expressed. Present in osteoclasts (at protein level).
Similarity:
Contains 3 ANK repeats.
Contains 1 SH3 domain.
SWISS:
Q92882
Gene ID:
26578
Database links:Entrez Gene: 427258 Chicken
Entrez Gene: 464532 Chimpanzee
Entrez Gene: 100063925 Horse
Entrez Gene: 26578 Human
Entrez Gene: 20409 Mouse
Entrez Gene: 703986 Rhesus monkey
Entrez Gene: 380103 Xenopus laevis
Entrez Gene: 549189 Xenopus tropicalis
Omim: 610180 Human
SwissProt: Q92882 Human
SwissProt: Q62422 Mouse
SwissProt: Q7ZYG4 Xenopus laevis
Unigene: 494192 Human
Unigene: 172222 Mouse
Unigene: 108470 Rat
Unigene: 7905 Xenopus laevis
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