Product Name	OSTF1
Chinese Name	破骨细胞刺激因子1抗体
Alias	bA235O14.1; FLJ20559; OSF; Osteoclast stimulating factor 1; Osteoclast-stimulating factor 1; Ostf1; OSTF1_HUMAN; SH3P2.
Research Area	Cell biology  Developmental biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	24kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human OSTF1: 101-200/214
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).[supplied by OMIM, Mar 2008] Function: Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitously expressed. Present in osteoclasts (at protein level). Similarity: Contains 3 ANK repeats. Contains 1 SH3 domain. SWISS: Q92882 Gene ID: 26578 Database links: Entrez Gene: 427258 Chicken Entrez Gene: 464532 Chimpanzee Entrez Gene: 281961 Cow Entrez Gene: 100063925 Horse Entrez Gene: 26578 Human Entrez Gene: 20409 Mouse Entrez Gene: 397066 Pig Entrez Gene: 259275 Rat Entrez Gene: 703986 Rhesus monkey Entrez Gene: 380103 Xenopus laevis Entrez Gene: 549189 Xenopus tropicalis Omim: 610180 Human SwissProt: Q8MJ50 Cow SwissProt: Q92882 Human SwissProt: Q62422 Mouse SwissProt: Q8MJ49 Pig SwissProt: Q6P686 Rat SwissProt: Q7ZYG4 Xenopus laevis Unigene: 494192 Human Unigene: 172222 Mouse Unigene: 108470 Rat Unigene: 7905 Xenopus laevis

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