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Product Name OSBPL6 Chinese Name 氧固醇Binding protein样6抗体 Alias FLJ36583; ORP 6; ORP-6; ORP6; OSBL6_HUMAN; OSBP-related protein 6; OSBPL 6; Osbpl6; Oxysterol Binding Protein like 6; Oxysterol-binding protein-related protein 6. Research Area Cell biology Signal transduction transcriptional regulatory factor The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, (predicted: Human, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 106kDa Cellular localization The nucleus cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OSBPL6: 261-360/934 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Tissue Specificity:
Widely expressed.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the OSBP family.
Contains 1 PH domain.
SWISS:
Q9BZF3
Gene ID:
114880
Database links:Entrez Gene: 114880 Human
Entrez Gene: 99031 Mouse
Omim: 606734 Human
SwissProt: Q9BZF3 Human
SwissProt: Q8BXR9 Mouse
Unigene: 318775 Human
Unigene: 728914 Human
Unigene: 240435 Mouse
Unigene: 15167 Rat
Product Picture Sample:
Muscle (Mouse) Lysate at 40 ug
Primary: Anti-OSBPL6 (SL17520R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 106 kD
Observed band size: 106 kD
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (OSBPL6) Polyclonal Antibody, Unconjugated (SL17520R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (OSBPL6) Polyclonal Antibody, Unconjugated (SL17520R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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