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Product Name SIX homeobox 4 Chinese Name 同源盒蛋白SIX4抗体 Alias AREC 3; AREC3; Homeobox protein SIX4; MGC119450; MGC119452; MGC119453; Sine oculis homeobox homolog 4; SIX4; SIX4_HUMAN. Research Area Cell biology Developmental biology Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, Guinea Pig, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 83kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SIX homeobox 4: 701-781/781 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. [provided by RefSeq, May 2010]
Subcellular Location:
Nucleus.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the SIX/Sine oculis homeobox family.
Contains 1 homeobox DNA-binding domain.
SWISS:
Q9UIU6
Gene ID:
51804
Database links:Entrez Gene: 51804 Human
Entrez Gene: 20474 Mouse
Omim: 606342 Human
SwissProt: Q9UIU6 Human
SwissProt: Q61321 Mouse
Unigene: 690393 Human
Unigene: 97849 Human
Unigene: 249575 Mouse
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