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Product Name HORMAD1 Chinese Name HORMAD1蛋白抗体 Alias Cancer/testis antigen CT46; CT46; HORMA domain containing 1; HORMA domain containing protein; Newborn ovary HORMA protein; NOHMA; OTTHUMP00000032933; RP11-363I22 1. Research Area Tumour Cell biology Cell type markers Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 45kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HORMAD1: 301-394/394 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Function:
HORMAD1 is a cancer/testis (CT) antigen; it is expressed strongly in testis, where it is increased in cancer and weakly in placenta. HORMAD1 shows homology to a yeast meiosis specific protein.
Subcellular Location:
Nuclear
SWISS:
Q86X24
Gene ID:
84072
Database links:
Entrez Gene: 84072 Human
Omim: 609824 Human
SwissProt: Q4R8B9 Cynomolgus Monkey
SwissProt: Q86X24 Human
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