Product Name	TOM1
Chinese Name	TOM1蛋白抗体
Alias	FLJ33404; OTTHUMP00000028777; Target of myb 1; TOM1_HUMAN； Target of Myb protein 1; Target of myb1; TOM 1.
Research Area	Cell biology  transcriptional regulatory factor  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Chimpanzee, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	54kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TOM1: 1-100/492
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] Function: TOM1 may be involved in intracellular trafficking. In conjunction with Tollip it plays an important role in recruiting clathrin onto endosomes and may modulate endosomal functions. Subunit: Interacts with ZFYVE16; interaction is required to target it to endosomes. Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein Tissue Specificity: Widely expressed. Highly expressed in skeletal muscle, heart, placenta and liver Similarity: Belongs to the TOM1 family. Contains 1 GAT domain. Contains 1 VHS domain. SWISS: O60784 Gene ID: 10043 Database links: Entrez Gene: 10043 Human Entrez Gene: 608746 Dog Entrez Gene: 21968 Mouse Entrez Gene: 361370 Rat Entrez Gene: 717499 Rhesus monkey Omim: 604700 Human SwissProt: O60784 Human SwissProt: O88746 Mouse SwissProt: Q5XI21 Rat

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