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Rabbit Anti-KIF24 antibody
Rabbit Anti-KIF24 antibody
bA571F15.4; C9orf48; Kif24; KIF24_HUMAN; kinesin family member 24; Kinesin-like protein KIF24; RP11-571F15.7.
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  • NO.:SL17051R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Horse,Rabbit,)
    Applications:ELISA
    concentration:1mg/ml
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Product Name KIF24
Chinese Name 驱动蛋白家族成员24抗体
Alias bA571F15.4; C9orf48; Kif24; KIF24_HUMAN; kinesin family member 24; Kinesin-like protein KIF24; RP11-571F15.7.  
Research Area Cell biology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
Applications ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 152kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human KIF24: 361-460/1368 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Kinesins, such as KIF24, are microtubule-dependent ATPases that function as molecular motors. They play important roles in intracellular vesicle transport and cell division (summary by Venturelli et al., 2010 [PubMed 20670673]).[supplied by OMIM, Feb 2011]

Function:
Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation.

Subunit:
Interacts with CCP110 and CEP97.

Subcellular Location:
Cytoplasm; cytoskeleton.

Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.
Contains 1 SAM (sterile alpha motif) domain.

SWISS:
Q5T7B8

Gene ID:
347240

Database links:

Entrez Gene: 347240 Human

Omim: 613747 Human

SwissProt: Q5T7B8 Human

Unigene: 710246 Human



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