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Product Name KIF24 Chinese Name 驱动蛋白家族成员24抗体 Alias bA571F15.4; C9orf48; Kif24; KIF24_HUMAN; kinesin family member 24; Kinesin-like protein KIF24; RP11-571F15.7. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 152kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human KIF24: 361-460/1368 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Kinesins, such as KIF24, are microtubule-dependent ATPases that function as molecular motors. They play important roles in intracellular vesicle transport and cell division (summary by Venturelli et al., 2010 [PubMed 20670673]).[supplied by OMIM, Feb 2011]
Function:
Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation.
Subunit:
Interacts with CCP110 and CEP97.
Subcellular Location:
Cytoplasm; cytoskeleton.
Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.
Contains 1 SAM (sterile alpha motif) domain.
SWISS:
Q5T7B8
Gene ID:
347240
Database links:Entrez Gene: 347240 Human
Omim: 613747 Human
SwissProt: Q5T7B8 Human
Unigene: 710246 Human
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