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Product Name TRIM29 (acetyl K116) Chinese Name 乙酰化TRIM29蛋白抗体 Alias Ataxia telangiectasia group D associated protein; Ataxia telangiectasia group D-associated protein; ATDC; FLJ36085; TRI29_HUMAN; TRIM 29; TRIM29; Tripartite motif containing 29; Tripartite motif containing protein 29; Tripartite motif protein 29; Tripartite motif protein TRIM29; Tripartite motif-containing protein 29. Product Type Acetylated anti Research Area Cell biology immunology Signal transduction transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Pig, Cow, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 66kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated Synthesised acetylpeptide derived from human TRIM29 around the acetylation site of K116: AK(Ac-K)PP Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]
Function:
It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.
Subcellular Location:
Cytoplasm. Colocalizes with intermediate filaments.
Tissue Specificity:
Expressed in placenta, prostate and thymus.
Post-translational modifications:
Constitutively phosphorylated by PKC on serine/threonine in A431 cells.
Similarity:
Contains 1 B box-type zinc finger.
SWISS:
Q14134
Gene ID:
23650
Database links:Entrez Gene: 23650 Human
Entrez Gene: 72169 Mouse
Omim: 610658 Human
SwissProt: Q14134 Human
SwissProt: Q8R2Q0 Mouse
Unigene: 504115 Human
Unigene: 273277 Mouse
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