Product Name	IRGC
Chinese Name	IRGC蛋白抗体
Alias	F630044M05Rik; Gm1102; Gm474; IIGP5; IIGP5_HUMAN; Immunity-related GTPase cinema 1; Interferon-inducible GTPase 5; IRGC; IRGC1; RGD1311107.
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	50kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IRGC: 301-400/463
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	IRGC (Immunity Related GTPase Cinema) is a Protein Coding gene. Diseases associated with IRGC include Solar Retinopathy and Echolalia. GO annotations related to this gene include GTP binding and hydrolase activity, acting on acid anhydrides. An important paralog of this gene is IRGM. Similarity: Belongs to the interferon-inducible GTPase family. SWISS: Q6NXR0 Gene ID: 56269 Database links: Entrez Gene: 56269 Human Entrez Gene: 210145 Mouse Entrez Gene: 308428 Rat SwissProt: Q6NXR0 Human SwissProt: Q8C262 Mouse SwissProt: Q6AYF9 Rat Unigene: 515444 Human Unigene: 33811 Mouse Unigene: 155129 Rat
Product Picture	Sample: A549 Cell (Human) Lysate at 30 ug Primary: Anti-IRGC (SL16706R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kD Observed band size: 50 kD Tissue/cell: Rat testis tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-IRGC Polyclonal Antibody, Unconjugated(SL16706R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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