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Product Name IMPG1 Chinese Name IMPG1蛋白抗体 Alias IPM150; GP147; IMPG1; IMPG1_HUMAN; Interphotoreceptor matrix proteoglycan 1; Interphotoreceptor matrix proteoglycan of 150 kDa; IPM-150; IPM150; Sialoprotein associated with cones and rods; SPACR. Research Area Cell biology immunology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 87kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IMPG1: 601-700/797 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a protein that is a major component of the retinal interphotoreceptor matrix. The encoded protein is a proteoglycan that is thought to play a role in maintaining viability of photoreceptor cells and in adhesion of the neural retina to the retinal pigment epithelium. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Function:
May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix.
Subcellular Location:
Secreted.
Tissue Specificity:
Abundantly expressed in retina where it is specifically expressed by cone and rod photoreceptor cells. Localizes to cone and rod photoreceptor cells surrounding the interphotoreceptor matrix of the retina.
Post-translational modifications:
The N-terminus is blocked.
Highly glycosylated (N- and O-linked carbohydrates and sialic acid).
Similarity:
Contains 2 SEA domains.
SWISS:
Q17R60
Gene ID:
3617
Database links:Entrez Gene: 3617 Human
Entrez Gene: 63859 Mouse
Omim: 602870 Human
SwissProt: Q17R60 Human
SwissProt: Q8R1W8 Mouse
Unigene: 590893 Human
Unigene: 422780 Mouse
Unigene: 64488 Rat
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