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Rabbit Anti-IMPG1 antibody
Rabbit Anti-IMPG1 antibody
IPM150; GP147; IMPG1; IMPG1_HUMAN; Interphotoreceptor matrix proteoglycan 1; Interphotoreceptor matrix proteoglycan of 150 kDa; IPM-150; IPM150; Sialoprotein associated with cones and rods; SPACR.
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  • NO.:SL16626R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name IMPG1
Chinese Name IMPG1蛋白抗体
Alias IPM150; GP147; IMPG1; IMPG1_HUMAN; Interphotoreceptor matrix proteoglycan 1; Interphotoreceptor matrix proteoglycan of 150 kDa; IPM-150; IPM150; Sialoprotein associated with cones and rods; SPACR.  
Research Area Cell biology  immunology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 87kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human IMPG1: 601-700/797 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a protein that is a major component of the retinal interphotoreceptor matrix. The encoded protein is a proteoglycan that is thought to play a role in maintaining viability of photoreceptor cells and in adhesion of the neural retina to the retinal pigment epithelium. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Function:
May interact with hyaluronan which may serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix.

Subcellular Location:
Secreted.

Tissue Specificity:
Abundantly expressed in retina where it is specifically expressed by cone and rod photoreceptor cells. Localizes to cone and rod photoreceptor cells surrounding the interphotoreceptor matrix of the retina.

Post-translational modifications:
The N-terminus is blocked.
Highly glycosylated (N- and O-linked carbohydrates and sialic acid).

Similarity:
Contains 2 SEA domains.

SWISS:
Q17R60

Gene ID:
3617

Database links:

Entrez Gene: 3617 Human

Entrez Gene: 63859 Mouse

Entrez Gene: 66014 Rat

Omim: 602870 Human

SwissProt: Q17R60 Human

SwissProt: Q8R1W8 Mouse

SwissProt: Q9ET62 Rat

Unigene: 590893 Human

Unigene: 422780 Mouse

Unigene: 64488 Rat



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