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Product Name IMPA2 Chinese Name 肌醇单磷酸酶2抗体 Alias IMP 2; IMP A2; IMP.18P; IMP2; IMPA 2; Impa2; IMPA2_HUMAN; IMPase 2; Inosine monophosphatase 2; Inositol 1; Inositol 1(or 4) monophosphatase 2; Inositol monophosphatase 2; Inositol monophosphatase 2 variant 1; Inositol monophosphatase 2 variant 2; Inositol(myo) 1(or 4) monophosphatase 2; Inositol-1(or 4)-monophosphatase 2; Myo inositol monophosphatase A2; Myo-inositol monophosphatase A2. Research Area Tumour Cell biology Neurobiology Signal transduction Kinases and Phosphatases The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Rabbit, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 31kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IMPA2: 1-100/288 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This locus encodes an inositol monophosphatase. The encoded protein catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling. This locus may be associated with susceptibility to bipolar disorder. [provided by RefSeq, Jan 2011]
Function:
Can use myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. Has been implicated as the pharmacological target for lithium Li(+) action in brain.
Similarity:
Belongs to the inositol monophosphatase family.
SWISS:
O14732
Gene ID:
3613
Database links:Entrez Gene: 3613 Human
Entrez Gene: 114663 Mouse
Omim: 605922 Human
SwissProt: O14732 Human
SwissProt: Q91UZ5 Mouse
Unigene: 723890 Human
Unigene: 726124 Human
Unigene: 34079 Mouse
Unigene: 441590 Mouse
Unigene: 856 Rat
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