Product Name	Integrin beta 8
Chinese Name	整合素β8抗体
Alias	Integrin beta-8; ITB8_HUMAN; ITGB 8; ITGB8.
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Pig, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	81kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Integrin beta 8: 301-400/769 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] Function: Integrin alpha-V/beta-8 is a receptor for fibronectin. Subcellular Location: Membrane. Tissue Specificity: Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells. Similarity: Belongs to the integrin beta chain family. Contains 1 VWFA domain. SWISS: P26012 Gene ID: 3696 Database links: Entrez Gene: 3696 Human Entrez Gene: 536286 Cow Entrez Gene: 475253 Dog Entrez Gene: 320910 Mouse Entrez Gene: 100037284 Pig Entrez Gene: 100009141 Rabbit Entrez Gene: 362800 Rat Omim: 604160 Human SwissProt: P26012 Human SwissProt: P26013 Rabbit Unigene: 592171 Human

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