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Product Name TRAPPC6A Chinese Name TRAPPC6A蛋白抗体 Alias 1810073E21Rik; 4930519D19Rik; AI480686; HSPC289; MGC117907; mhyp; OTTMUSP00000025165; OTTMUSP00000025166; rCG_54352; RGD1309160; TPC6A_HUMAN; Trafficking protein particle complex 6A; Trafficking protein particle complex subunit 6A; TRAPP complex subunit 6A; TRAPPC6A; TRS33. literatures Specific References (1) | SL16587R has been referenced in 1 publications.[IF=3.687] Yuan FH et al. microRNA‐30a inhibits the liver cell proliferation and promotes cell apoptosis through the JAK/STAT signaling pathway by targeting SOCS‐1 in rats with sepsis. J Cell Physiol. 2019 Apr 10. WB ; Rat.Research Area Cell biology Signal transduction Transporter Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Dog, Horse, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 18kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TRAPPC6A: 21-100/159 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail TRAPPC6A is a 159 amino acid protein that localizes to the Golgi apparatus and endoplasmic reticulum. Belonging to the TRAPP small subunits family and the BET3 subfamily, TRAPPC6A may play a role in vesicular transport during the biogenesis of melanosomes. TRAPPC6A is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor. TRAPPC6A exists as a heterodimer with TRAPPC3 and undergoes alternative splicing to produce two isoforms. TRAPPC6A is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a variety of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).
Function:
May play a role in vesicular transport during the biogenesis of melanosomes.
Subunit:
Part of the multisubunit TRAPP (transport protein particle) complex. Heterodimer with TRAPPC3. The heterodimer TRAPPC3-TRAPPC6A interacts with TRAPPC2L. Interacts with TRAPPC2L.
Subcellular Location:
Golgi apparatus; cis-Golgi network. Endoplasmic reticulum.
Similarity:
Belongs to the TRAPP small subunits family. BET3 subfamily.
SWISS:
O75865
Gene ID:
79090
Database links:Entrez Gene: 79090 Human
Omim: 610396 Human
SwissProt: O75865 Human
Unigene: 466929 Human
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