TEL: +86 571 56623320 EMAIL: [email protected]
Product Name TRAF3IP3 Chinese Name T3JAM蛋白抗体 Alias T3JAM; TRAF3 interacting JNK activating modulator; T3JAM_HUMAN; TRAF3 interacting protein 3. Research Area Cell biology Signal transduction Transmembrane protein Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 64kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TRAF3IP3: 501-551/551 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Function:
This protein may function as an adapter molecule that regulates TRAF3-mediated JNK activation.
Subunit:
Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain (By similarity).
Subcellular Location:
Membrane; single pass type IV membrane protein
SWISS:
Q9Y228
Gene ID:
80342
Database links:Entrez Gene: 80342 Human
SwissProt: Q9Y228 Human
SwissProt: Q8C0G2 Mouse
Unigene: 147434 Human
Unigene: 261259 Mouse
Scan Wechat Qrcode