Product Name	HECTD4
Chinese Name	HECTD4蛋白抗体
Alias	C12orf51; HECT domain-containing protein 4; HECTD4; HECD4_HUMAN; KIAA0614; Probable E3 ubiquitin-protein ligase HECTD4.
Research Area	Cell biology  Ubiquitin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	439kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HECTD4: 21-120/3996
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity). Subcellular Location: Membrane; Single-pass membrane protein Similarity: Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. SWISS: Q9Y4D8 Gene ID: 283450 Database links: Entrez Gene: 283450 Human SwissProt: Q9Y4D8 Human

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