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Product Name ZNF8 Chinese Name Zinc finger protein8抗体 Alias HF.18; Zfp128; Zinc finger protein 272; Zinc finger protein 8 (clone HF.18); Zinc finger protein 8; Zinc finger protein HF.18; ZNF 8; ZNF8; ZNF8_HUMAN. Research Area transcriptional regulatory factor Zinc finger protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Human, Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 65kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZNF8: 121-220/575 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ZNF8 is a 575 amino acid protein that belongs to the Krüppel C2H2-type zinc-finger protein family and contains seven C2H2-type zinc fingers and a KRAB domain. Localizing to the nucleus and ubiquitously expressed, ZNF8 is thought to play a role in transcriptional regulation and is encoded by a gene that maps to human chromosome 19q13.43.
Function:
May be involved in transcriptional regulation.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitously present in many human cell lines of different embryological derivation.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 7 C2H2-type zinc fingers.
Contains 1 KRAB domain.
SWISS:
P17098
Gene ID:
7554
Database links:Entrez Gene: 7554 Human
Omim: 194532 Human
SwissProt: P17098 Human
Unigene: 590941 Human
Unigene: 713519 Human
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