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Product Name ZNF827 Chinese Name Zinc finger protein827抗体 Alias Zfp827; Zinc finger protein 827; ZN827_HUMAN; ZNF827. Research Area transcriptional regulatory factor Zinc finger protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 119kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZNF827: 1-100/1081 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ZNF827 (zinc finger protein 827) is a 1,081 amino acid nuclear protein that contains nine C2H2-type zinc fingers and belongs to the krueppel C2H2-type zinc-finger protein family. Existing as three alternatively spliced isoforms, ZNF827 may be involved in transcriptional regulation. The gene that encodes ZNF827 consists of around 181,000 bases and maps to human chromosome 4q31.2. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is encoded by a gene that maps to chromosome 4. FGFR-3 is also encoded by a gene located on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Function:
May be involved in transcriptional regulation.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 9 C2H2-type zinc fingers.
SWISS:
Q17R98
Gene ID:
152485
Database links:Entrez Gene: 152485 Human
Entrez Gene: 622675 Mouse
SwissProt: Q17R98 Human
SwissProt: Q505G8 Mouse
Unigene: 133916 Human
Unigene: 48724 Mouse
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