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Product Name ZNFN1A2 Chinese Name ZNFN1A2蛋白抗体 Alias ANF1A2; HELIOS; IKAROS family zinc finger 2; Ikaros family zinc finger protein 2; IKZF 2; IKZF2; IKZF2_HUMAN; MGC34330; Zinc finger DNA binding protein Helios; Zinc finger protein Helios; zinc finger protein subfamily 1A 2; ZNF1A2. Research Area Cell biology Developmental biology transcriptional regulatory factor lymphocyte t-lymphocyte Zinc finger protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 60kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZNFN1A2: 21-120/526 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Function:
Associates with Ikaros at centromeric heterochromatin.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the Ikaros C2H2-type zinc-finger protein family.
Contains 6 C2H2-type zinc fingers.
SWISS:
Q9UKS7
Gene ID:
22807
Database links:Entrez Gene: 22807 Human
Entrez Gene: 22779 Mouse
Omim: 606234 Human
SwissProt: Q9UKS7 Human
SwissProt: P81183 Mouse
Unigene: 604950 Human
Unigene: 106343 Mouse
Unigene: 229574 Rat
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