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Product Name ZNT6 Chinese Name ZNT6蛋白抗体 Alias FLJ31101; MSTP103; SLC30A6; Solute carrier family 30 (zinc transporter), member 4; Solute carrier family 30 (zinc transporter), member 6; Solute carrier family 30 member 6; Zinc transporter 6; Zinc transporter like 3; ZnT-6; ZnT6; ZNT6_HUMAN. Research Area Tumour Cell biology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 51kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZNT6: 301-400/461 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A6, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008]
Function:
Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.
Subcellular Location:
Golgi apparatus > trans-Golgi network membrane. Found in vesicules.
Tissue Specificity:
Expressed in brain; especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis.
Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4)
family. SLC30A subfamily.
SWISS:
Q6NXT4
Gene ID:
55676
Database links:Entrez Gene: 55676 Human
Entrez Gene: 210148 Mouse
Omim: 611148 Human
SwissProt: Q6NXT4 Human
SwissProt: Q8BJM5 Mouse
Unigene: 23248 Human
Unigene: 243943 Mouse
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