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Rabbit Anti-ZNT6 antibody
Rabbit Anti-ZNT6 antibody
FLJ31101; MSTP103; SLC30A6; Solute carrier family 30 (zinc transporter), member 4; Solute carrier family 30 (zinc transporter), member 6; Solute carrier family 30 member 6; Zinc transporter 6; Zinc transporter like 3; ZnT-6; ZnT6; ZNT6_HUMAN.
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  • NO.:SL16414R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name ZNT6
Chinese Name ZNT6蛋白抗体
Alias FLJ31101; MSTP103; SLC30A6; Solute carrier family 30 (zinc transporter), member 4; Solute carrier family 30 (zinc transporter), member 6; Solute carrier family 30 member 6; Zinc transporter 6; Zinc transporter like 3; ZnT-6; ZnT6; ZNT6_HUMAN.  
Research Area Tumour  Cell biology  Signal transduction  The new supersedes the old  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 51kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ZNT6: 301-400/461 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A6, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008]

Function:
Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.

Subcellular Location:
Golgi apparatus > trans-Golgi network membrane. Found in vesicules.

Tissue Specificity:
Expressed in brain; especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis.

Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4)
family. SLC30A subfamily.

SWISS:
Q6NXT4

Gene ID:
55676

Database links:

Entrez Gene: 55676 Human

Entrez Gene: 210148 Mouse

Omim: 611148 Human

SwissProt: Q6NXT4 Human

SwissProt: Q8BJM5 Mouse

Unigene: 23248 Human

Unigene: 243943 Mouse



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