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Rabbit Anti-GSH2 antibody
Rabbit Anti-GSH2 antibody
GS homeobox 2; GSX2; GSX2_HUMAN; Homeobox protein GSH 2; Homeobox protein GSH-2.
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  • NO.:SL16336R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name GSH2
Chinese Name GSH2蛋白抗体
Alias GS homeobox 2; GSX2; GSX2_HUMAN; Homeobox protein GSH 2; Homeobox protein GSH-2.  
Research Area Cell biology  Transporter  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 32kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GSH2: 211-304/304 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure. The homeobox DNA-binding domain is commonly found in proteins that play a role in development and are involved in transcriptional regulation and the control of gene expression. GSH-2 (GS homeobox-2), also known as GSX2, is a 304 amino acid protein that contains one homeobox DNA-binding domain. Localized to the nucleus, GSH-2 is thought to function as a transcription factor that selectively binds the DNA sequence 5'-CNAATTAG-3'. Specifically, GSH-2 may be involved in neuronal differentiation, playing a role in spinal cord development.

Function:
Probable transcription factor that binds to the DNA sequence 5'-CNAATTAG-3' (By similarity).

Subcellular Location:
Nucleus (By similarity).

Similarity:
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain.

SWISS:
Q9BZM3

Gene ID:
170825

Database links:

Entrez Gene: 170825 Human

Entrez Gene: 14843 Mouse

Entrez Gene: 364140 Rat

SwissProt: Q9BZM3 Human

SwissProt: P31316 Mouse

Unigene: 371899 Human

Unigene: 218752 Mouse



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