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Product Name FOXL1 Chinese Name FOXL1蛋白抗体 Alias FKH 6; FKH6; FKHL 11; FKHL11; Forkhead (Drosophila) like 11; Forkhead box L1; Forkhead box protein L1; Forkhead related protein FKHL11; Forkhead related transcription factor 7; Forkhead-related protein FKHL11; Forkhead-related transcription factor 7; FOX L1; FOXL 1; Foxl1; FOXL1_HUMAN; FREAC 7; FREAC-7; FREAC7. Research Area Cell biology immunology Signal transduction transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 36kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FOXL1: 201-300/345 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012]
Function:
Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors (By similarity).
Subcellular Location:
Nucleus.
Similarity:
Contains 1 fork-head DNA-binding domain.
SWISS:
Q12952
Gene ID:
2300
Database links:Entrez Gene: 2300 Human
Entrez Gene: 14241 Mouse
Omim: 603252 Human
SwissProt: Q12952 Human
SwissProt: Q64731 Mouse
Unigene: 533830 Human
Unigene: 5111 Mouse
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