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Product Name FOXJ3 Chinese Name FOXJ3蛋白抗体 Alias Forkhead box J3; Forkhead box protein J3; FOXJ3; FOXJ3_HUMAN; KIAA1041; MGC165036; MGC176686. Research Area Cell biology transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 69kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FOXJ3: 121-220/622 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail FOXJ3 (forkhead box protein J3) is a 622 amino acid protein encoded by the human gene FOXJ3. FOXJ3, having one forkhead DNA-binding domain, is a novel forkhead factor and, as such, belongs to the forkhead protein family. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. Forkhead factors are known to play important roles both during development and in adults. FOXJ3 is expressed in neuroectoderm, in neural crest, and in many structures derived from neural crest cells, such as facioacoustic, trigeminal and dorsal root ganglia. Stripes of FOXJ3 expression appear in the location of myotomes and expand ventrally in a pattern similar to the developing body wall musculature. Developing limbs have a complex pattern of FOXJ3 expression that at E12.5 colocalizes with the condensed mesenchyme of the skeletal primordia.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 fork-head DNA-binding domain.
SWISS:
Q9UPW0
Gene ID:
22887
Database links:Entrez Gene: 22887 Human
Entrez Gene: 230700 Mouse
SwissProt: Q9UPW0 Human
SwissProt: Q8BUR3 Mouse
Unigene: 26023 Human
Unigene: 259227 Mouse
Unigene: 202994 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FOXJ3) Polyclonal Antibody, Unconjugated (SL16167R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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