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Rabbit Anti-RNF207 antibody
Rabbit Anti-RNF207 antibody
FLJ46380;C1orf188; D330010C22Rik; FLJ32096; FLJ46380; FLJ46593; Gm143; Ring finger protein 207; RN207_HUMAN; RNF 207; RNF207; RP23-421E12.8.
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  • NO.:SL16145R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)
    Applications:IHC-P IHC-F ICC IF
    concentration:1mg/ml
  • Goods click count:29
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Details

Product Name RNF207
Chinese Name Ring finger protein207抗体
Alias FLJ46380; C1orf188; D330010C22Rik; FLJ32096; FLJ46380; FLJ46593; Gm143; Ring finger protein 207; RN207_HUMAN; RNF 207; RNF207; RP23-421E12.8.  
Research Area Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 71kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human RNF207: 211-310/634 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Similarity:
Contains 1 B box-type zinc finger.
Contains 1 RING-type zinc finger.

SWISS:
Q6ZRF8

Gene ID:
388591

Database links:

Entrez Gene: 388591 Human

Entrez Gene: 433809 Mouse

Entrez Gene: 691246 Rat

SwissProt: Q6ZRF8 Human

SwissProt: Q3V3A7 Mouse

Unigene: 716549 Human

Unigene: 156205 Mouse



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