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Rabbit Anti-Neun , Alexa Flour 680 conjugated antibody
Rabbit Anti-Neun , Alexa Flour 680 conjugated antibody
RFOX3_HUMAN; RNA binding protein fox-1 homolog 3; RBFOX3; Fox-1 homolog C; Neuronal nuclei antigen (NeuN antigen); FOX3; NEUN; FOX-3; HRNBP3;
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  • NO.:SL1613R-AF680
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,)
    Applications:IF
    concentration:1mg/ml
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Details

Product Name NeuN, Alexa Flour 680 conjugated
Chinese Name AF680标记的神经元核抗原抗体
Alias RFOX3_HUMAN; RNA binding protein fox-1 homolog 3; RBFOX3; Fox-1 homolog C; Neuronal nuclei antigen (NeuN antigen); FOX3; NEUN; FOX-3; HRNBP3;  
Research Area Cell biology  Neurobiology  Transporter  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, )
Applications IF=1:100-500 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 34kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human NeuN: 51-150/312 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]

Function:
RNA-binding protein that regulates alternative splicing events.

Subcellular Location:
Nucleus. Cytoplasm.

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
A6NFN3

Gene ID:
146713

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