Product Name	FGD6
Chinese Name	FGD6蛋白抗体
Alias	FYVE, RhoGEF and PH domain containing protein 6; ZFYVE24; FGD6_HUMAN; Zinc finger FYVE domain containing protein 24.
Research Area	Cell biology  immunology  Signal transduction  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	161kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FGD6: 1331-1430/1430
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	FGD6 is a 1,430 amino acid cytoplasmic protein that belongs to the FGD family and exists as two alternatively spliced isoforms. Thought to activate Cdc42 by exchanging bound GDP for free GTP, FGD6 is also implicated in maintenance of the actin cytoskeleton and regulating cell shape. Encoded by a gene that maps to human chromosome 12q22, FGD6 contains one FYVE-type zinc finger, two PH domains and a single DH (DBL-homology) domain. Function: FGD6 may activate CDC42 by exchanging bound GDP for free GTP. It may also play a role in regulating the actin cytoskeleton and cell shape. There are two isoforms. Subcellular Location: Cytoplasm (Probable). Cytoplasm, cytoskeleton (Probable). SWISS: Q6ZV73 Gene ID: 55785 Database links: Entrez Gene: 55785 Human SwissProt: Q6ZV73 Human Unigene: 506381 Human

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