Product Name	FBXW9
Chinese Name	FBXW9蛋白抗体
Alias	F box and WD 40 domain containing protein 9; F box/WD repeat containing protein 9; F-box and WD-40 domain-containing protein 9; F-box/WD repeat-containing protein 9; FBW9; FBXW9; FBXW9_HUMAN; Specificity factor for SCF ubiquitin ligase.
Research Area	Cell biology  Stem cells  Epigenetics  Ubiquitin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	54kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FBXW9: 201-300/488
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Members of the F-box protein family, such as FBXW9, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Similarity: Contains 1 F-box domain. Contains 7 WD repeats. SWISS: Q5XUX1 Gene ID: 84261 Database links: Entrez Gene: 84261 Human Omim: 609074 Human SwissProt: Q5XUX1 Human Unigene: 515154 Human
Product Picture	Sample: A431 Cell (Human) Lysate at 30 ug Primary: Anti- FBXW9 (SL16055R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kD Observed band size: 54 kD

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