Product Name	IBP160
Chinese Name	160kDa内含子Binding protein抗体
Alias	AQR; AQR_HUMAN; aquarius; aquarius homolog (mouse); DKFZp686B23123; fSAP164; functional spliceosome-associated protein 164; IBP160; Intron-binding protein aquarius; Intron-binding protein of 160 kDa; KIAA0560.
Research Area	Chromatin and nuclear signals  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	171kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IBP160: 1-100/1485
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. Subunit: Identified in the spliceosome C complex. Subcellular Location: Nucleus. Note=Localizes to speckle-like regions of the nucleoplasm. Similarity: Belongs to the CWF11 family. SWISS: O60306 Gene ID: 9716 Database links: Entrez Gene: 9716 Human Omim: 610548 Human SwissProt: O60306 Human Unigene: 510958 Human

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