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Rabbit Anti-IFNK antibody
Rabbit Anti-IFNK antibody
IFN kappa; IFN-kappa; Ifnk; IFNK_HUMAN; Interferon kappa.
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  • NO.:SL15524R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name IFNK
Chinese Name Interferonkappa蛋白抗体
Alias IFN kappa; IFN-kappa; Ifnk; IFNK_HUMAN; Interferon kappa.   
Research Area Cell biology  cell factor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 22kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human IFNK: 51-150/207 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail IFNK is a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster.

Function:
May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in keratinocytes, monocytes and in resting dendritic cells.

Similarity:
Belongs to the alpha/beta interferon family.

SWISS:
Q9P0W0

Gene ID:
56832

Database links:

Entrez Gene: 56832 Human

Omim: 615326 Human

SwissProt: Q9P0W0 Human

Unigene: 591083 Human



Product Picture
Tissue/cell: human colon carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-IFNK Polyclonal Antibody, Unconjugated(SL15524R) 1:400, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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