Product Name	GPR92
Chinese Name	G protein-coupled receptorGPR92蛋白抗体
Alias	GPCR GPR92; G-protein coupled receptor 92; G-protein coupled receptor 93; GPR92; GPR93; KPG_010; LPA receptor 5; LPA-5; LPA5; LPAR5; Lysophosphatidic acid receptor 5; LPAR5_HUMAN; GPCR 92.
literatures	Specific References  (4)     |     SL15366R has been referenced in 4 publications. [IF=9.77] Tang Y et al. PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recoveryAutophagy.2020 Dec 15;1-18.  WB ;  Mouse.   PubMed:33317392 [IF=2.942] Xue Gang. et al. Identification of key genes of papillary thyroid carcinoma by integrated bioinformatics analysis. Bioscience Rep. 2020 Aug;40(8):BSR20201555  WB ;  Human.   PubMed:32766727 [IF=2.903] Xuling Zhang. et al. Effects of lysophosphatidic acid receptor 5 on NLRC4 inflammasome in brain tissues of transient cerebral ischemia/reperfusion rat:. Hum Exp Toxicol. 2022;():  IF ;  Rat.   PubMed:35230166 [IF=2.311] Bingsheng Yang. et al. Identification of prognostic biomarkers associated with metastasis and immune infiltration in osteosarcoma. Oncol Lett. 2021 Mar;21(3):1-1  IHC ;  Human.   PubMed:33574919
Research Area	Cell biology  immunology  Signal transduction  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	41kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GPR92: 121-220/372 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008] Function: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q9H1C0 Gene ID: 57121 Database links: Entrez Gene: 57121 Human Omim: 606926 Human SwissProt: Q9H1C0 Human Unigene: 155538 Human
Product Picture	Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Lane 3: Human K562 cell lysates Lane 4: Human A431 cell lysates Lane 5: Human Jurkat cell lysates Primary: Anti-GPR92 (SL15366R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kDa Observed band size: 46 kDa Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-GPR92 Polyclonal Antibody, Unconjugated(SL15366R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining Tissue/cell: rat lung tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-GPR92 Polyclonal Antibody, Unconjugated(SL15366R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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