Product Name	C9orf61
Chinese Name	9号染色体开放阅读框61抗体
Alias	Chromosome 9 open reading frame 61; Friedreich ataxia region gene X123; MGC142243; MGC142245; OTTHUMP00000063356; Protein X123; RP11 548B3.1; Uncharacterized protein C9orf61; X123; F1892_HUMAN.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	47kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human C9orf61: 351-450/450
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Friedreich's ataxia is an inherited disease that is characterized by a progressive degeneration of the spinal cord and nerve tissue. Caused by a mutated gene region on chromosome 9 that results in mitochondrial malfunction, Friedreich's ataxia can lead to a variety of conditions including speech problems, vision impairment, muscle weakness, diabetes and scoliosis. X123, also known as C9orf61 (chromosome 9 open reading frame 61), is a 289 amino acid protein that is expressed at high levels in skeletal muscle and at lower levels in brain, heart and lung. The gene encoding X123 is located within the Friedreich's ataxia region on chromosome 9, suggesting a possible role for X123 in the pathogenesis of this disease. Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Tissue Specificity: Prominently expressed in muscle. Similarity: Belongs to the FAM189 family. SWISS: Q15884 Gene ID: 9413 Database links: Entrez Gene: 9413 Human Omim: 607710 Human SwissProt: Q15884 Human Unigene: 118003 Human

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