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Product Name C6ORF182 Chinese Name 6号染色体开放阅读框182抗体 Alias BA487F23.2; Centrosomal protein of 57 kDa-related protein; Cep57-related protein; CEP57R; Chromosome 6 open reading frame 182; Hypothetical protein LOC285753; MGC21731; MGC70837; OTTHUMP00000016948;CE57L_HUMAN. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 54kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human C6ORF182: 131-230/460 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf182 gene product has been provisionally designated C6orf182 pending further characterization.
Function:
Centrosomal protein which may be required for microtubule attachment to centrosomes (By similarity).
Subcellular Location:
Cytoplasm, cytoskeleton, centrosome (By similarity).
Similarity:
Belongs to the translokin family.
SWISS:
Q8IYX8
Gene ID:
285753
Database links:Entrez Gene: 285753 Human
SwissProt: Q8IYX8 Human
Unigene: 632616 Human
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