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Product Name ERGIC2 Chinese Name ERGIC2蛋白抗体 Alias cd002; CD14 protein; CDA14; Endoplasmic reticulum Golgi intermediate compartment protein 2; Endoplasmic reticulum-Golgi intermediate compartment protein 2; ERGI2_HUMAN; ERGIC 2; ERGIC and golgi 2; ergic2; Erv41; MGC111152; PTX1; PTX1 protein. Research Area Cell biology Signal transduction transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, Guinea Pig, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 43kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ERGIC2: 31-130/377 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ERGIC2, or PTX1, is a ubiquitously expressed nuclear protein that is downregulated in prostate carcinoma (Kwok et al., 2001 [PubMed 11445006]).[supplied by OMIM, Aug 2008]
Function:
Possible role in transport between endoplasmic reticulum and Golgi.
Subcellular Location:
Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus > cis-Golgi network membrane. Endoplasmic reticulum membrane. Cytoplasm. Nucleus. Cycles between the endoplasmic reticulum and the Golgi. PubMed:11445006 states that it localizes to the nucleus; PubMed:17980171 shows a partial localization in the nucleus.
Tissue Specificity:
Ubiquitously expressed.
Similarity:
Belongs to the ERGIC family.
SWISS:
Q96RQ1
Gene ID:
51290
Database links:Entrez Gene: 51290 Human
Entrez Gene: 67456 Mouse
Entrez Gene: 393378 Zebrafish
Omim: 612236 Human
SwissProt: Q96RQ1 Human
SwissProt: Q9CR89 Mouse
SwissProt: Q7T2D4 Zebrafish
Unigene: 339453 Human
Unigene: 59812 Mouse
Unigene: 12056 Zebrafish
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