Product Name	TRAP1/HSP75
Chinese Name	热休克蛋白75抗体
Alias	TRAP1; TRAP-1; Heat shock protein 75; Heat shock protein 75 kDa mitochondrial; HSP 75; HSP 90L; HSP75; HSP90L; TNF receptor associated protein 1; TNFR associated protein 1; TRAP 1; Tumor necrosis factor receptor associated protein; Tumor necrosis factor type 1 receptor associated protein; TRAP1_HUMAN.
Research Area	Tumour  Cell biology  immunology  Signal transduction  Apoptosis  transcriptional regulatory factor  Mitochondrion
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	74kDa
Cellular localization	cytoplasmic Mitochondrion
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HSP75: 501-650/704
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] Function: Chaperone that expresses an ATPase activity. Subunit: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. Binds to RB1. Subcellular Location: Mitochondrion. Tissue Specificity: Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta. Similarity: Belongs to the heat shock protein 90 family. SWISS: Q12931 Gene ID: 10131 Database links: Entrez Gene: 10131 Human Entrez Gene: 68015 Mouse Entrez Gene: 287069 Rat Entrez Gene: 416666 Chicken Entrez Gene: 514472 Cow Omim: 606219 Human SwissProt: Q2TBI4 Cow SwissProt: Q12931 Human SwissProt: Q9CQN1 Mouse SwissProt: Q5XHZ0 Rat Unigene: 30345 Human Unigene: 123366 Mouse Unigene: 144695 Rat 信号传导（Signaling Intermediates） HSP75/TRAP-1与TNF受体发生相互作用,可产生促进TNF的Signal transduction。

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