Product Name	DEFB118
Chinese Name	防御素β-118/β-defensin 118抗体
Alias	beta 118; Beta-defensin 118; Beta-defensin 118 precursor; Beta-defensin 18; C20orf63; Chromosome 20 open reading frame 63; DB118_HUMAN; DEFB-18; DEFB118; Defensin; Defensin beta 18; Defensin, beta 118; Epididymal secretory protein 13.6; epididymus specific clone 42; ESC42; ESP13.6.
Research Area	Cell biology  immunology  Developmental biology  Bacteria and viruses
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	4.9kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DEFB118: 20-62/123
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. [provided by RefSeq, Dec 2010] Function: Has antibacterial activity. Subcellular Location: Secreted. Tissue Specificity: High-level and epididymis-specific expression. Most abundant in the epithelium of the caput and is also present in the lumen and bound to sperm. Expressed also in pancreas. Similarity: Belongs to the beta-defensin family. SWISS: Q96PH6 Gene ID: 117285 Database links: Entrez Gene: 117285 Human Omim: 607650 Human SwissProt: Q96PH6 Human Unigene: 274124 Human

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