Product Name	DEFB110
Chinese Name	防御素β-110/β-defensin 110抗体
Alias	Beta defensin 11; Beta defensin 110; Beta defensin 111; CBD110; DEFB 10; DEFB 11; DEFB 110; DEFB10; DEFB11; DEFB111; Defensin beta 10; Defensin beta 110; Defensin, beta 111; MGC183056; MGC190230.
Research Area	Cell biology  immunology  Developmental biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	5.7kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DEFB110: 20-67/67
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Beta-defensins are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. The family of Beta-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many Beta-defensins also are involved in sperm maturation and capacitation. Beta-defensin 110 is a 67 amino acid secreted protein that has antibacterial activity. There are two isoforms of Beta-defensin 110 that exist as a result of alternative splicing events. Function: DEFB110 belongs to the beta-defensin family. It has antibacterial activity. There are two named isoforms produced by alternative splicing. Subcellular Location: Secreted SWISS: Q30KQ9 Gene ID: 245913 Database links: Entrez Gene: 245913 Human SwissProt: Q30KQ9 Human Unigene: 571093 Human

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