Product Name	DDX59
Chinese Name	ATP依赖RNA解旋酶DDX59抗体
Alias	DDX 59; DDX59; DDX59_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 59; DEAD box protein 59; DKFZP564B1023; OTTHUMP00000033840; OTTHUMP00000033841; Probable ATP-dependent RNA helicase DDX59; RP11-92G12.2; Zinc finger HIT domain containing protein 5; Zinc finger HIT domain-containing protein 5; ZNHIT5.
Research Area	Developmental biology  transcriptional regulatory factor  Cell differentiation  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	69kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DDX59: 51-150/619
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX59 is a 619 amino acid member of the DEAD box helicase protein family. Like many DEAD box helicase family members, DDX59 contains a Q motif, which controls ATP binding and hydrolysis. Expressed as two isoforms produced by alternative splicing, DDX59 contains one helicase C-terminal domain and one HIT-type zinc finger. Similarity: Belongs to the DEAD box helicase family. DDX59 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Contains 1 HIT-type zinc finger. SWISS: Q5T1V6 Gene ID: 83479 Database links: Entrez Gene: 83479 Human SwissProt: Q5T1V6 Human Unigene: 497332 Human

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