Product Name	DDX52
Chinese Name	ATP依赖RNA解旋酶DDX52抗体
Alias	ATP dependent RNA helicase ROK1 like; ATP-dependent RNA helicase ROK1-like; DDX52; DDX52_HUMAN; DEAD (Asp-Glu-Ala-Asp) box polypeptide 52; DEAD box protein 52; Probable ATP dependent RNA helicase DDX52; Probable ATP-dependent RNA helicase DDX52; ROK1.
Research Area	Developmental biology  transcriptional regulatory factor  Cell differentiation  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	67kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DDX52: 501-599/599
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DEAD box protein 52 (DDX52) is a 599 amino acid protein belonging to the DEAD box helicase family. Localized to the nucleus, DDX52 is phosphorylated by ATM or ATR upon DNA damage. DDX52 contains one helicase ATP-binding domain and one helicase C-terminal domain Subcellular Location: Nucleus > nucleolus. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. SWISS: Q9Y2R4 Gene ID: 11056 Database links: Entrez Gene: 11056 Human Entrez Gene: 78394 Mouse Entrez Gene: 85432 Rat SwissProt: A5D7C1 Cow SwissProt: Q9Y2R4 Human SwissProt: Q8K301 Mouse SwissProt: Q99PT0 Rat Unigene: 51117 Cow Unigene: 590937 Human Unigene: 280544 Mouse Unigene: 18605 Rat

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