Product Name	MRP4/ABCC4
Chinese Name	多药耐药相关蛋白4抗体
Alias	ABCC 4; ABCC4; ATP binding cassette sub family C (CFTR/MRP) member 4; ATP binding cassette sub family C member 4; bA464I2.1 (ATP binding cassette, sub-family C (CFTR/MRP) member 4); bA464I2.1; Canalicular multispecific organic anion transporter; Canalicular multispecific organic anion transporter ABC superfamily; EST170205; MOAT B; MOATB; MRP 4; MRP/cMOAT related ABC transporter; Multi specific organic anion transporter B; Multidrug resistance associated protein 4; OTTHUMP00000018560; MRP4_HUMAN.
Research Area	Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Guinea Pig, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	149kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MRP4: 751-880/1325
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]. Function: May be an organic anion pump relevant to cellular detoxification. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed, with particularly high levels in prostate, but is barely detectable in liver. Similarity: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. Contains 2 ABC transmembrane type-1 domains. Contains 2 ABC transporter domains. SWISS: O15439 Gene ID: 10257 Database links: Entrez Gene: 10257 Human Entrez Gene: 239273 Mouse Omim: 605250 Human SwissProt: O15439 Human Unigene: 508423 Human Unigene: 40537 Mouse

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