Product Name	DDX24
Chinese Name	ATP依赖解旋酶DDX24抗体
Alias	ATP dependent RNA helicase DDX24; ATP-dependent RNA helicase ddx24; DDX 24; ddx24; DDX24_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 24; DEAD box protein 24; DEAD/H (Asp Glu Ala Asp) box polypeptide 24; S. cerevisiae CHL1 like helicase.
Research Area	Cardiovascular  Cell biology  Neurobiology  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	120kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DDX24: 701-800/859
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. [provided by RefSeq, Jul 2008] Function: ATP-dependent RNA helicase. Tissue Specificity: Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. SWISS: Q9GZR7 Gene ID: 57062 Database links: Entrez Gene: 57062 Human Entrez Gene: 27225 Mouse Omim: 606181 Human SwissProt: Q9GZR7 Human SwissProt: Q9ESV0 Mouse Unigene: 510328 Human Unigene: 3935 Mouse Unigene: 475067 Mouse

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