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Rabbit Anti-phospho-ETS2 (Thr72)antibody
Rabbit Anti-phospho-ETS2 (Thr72)antibody
ETS2 (phospho T72); p-ETS2 (phospho T72);ets 2 protein; ETS2; ETS2_HUMAN; ETS2IT1; Oncogene ETS2; Protein C-ets-2; v ets avian erythroblastosis virus E2 oncogene homolog 2; V ets erythroblastosis virus E26 oncogene homolog 2.
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  • NO.:SL14175R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,(predicted: Mouse,Rat,Cow,Sheep,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name phospho-ETS2 (Thr72)
Chinese Name 磷酸化癌基因ETS2抗体
Alias ETS2 (phospho T72); p-ETS2 (phospho T72); ets 2 protein; ETS2; ETS2_HUMAN; ETS2IT1; Oncogene ETS2; Protein C-ets-2; v ets avian erythroblastosis virus E2 oncogene homolog 2; V ets erythroblastosis virus E26 oncogene homolog 2.  
Product Type Phosphorylated anti 
Research Area Tumour  Cell biology  Signal transduction  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Cow, Sheep, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 70kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated Synthesised phosphopeptide derived from human ETS2 around the phosphorylation site of Thr72: LL(p-T)P 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Function:
Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.
Contains 1 PNT (pointed) domain.

SWISS:
P15036

Gene ID:
2114

Database links:

Entrez Gene: 2114 Human

Entrez Gene: 23872 Mouse

Entrez Gene: 304063 Rat

Omim: 164740 Human

SwissProt: P15036 Human

SwissProt: P15037 Mouse

Unigene: 644231 Human

Unigene: 290207 Mouse



Product Picture
Paraformaldehyde-fixed, paraffin embedded (human cervical cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ETS2 (Thr72)) Polyclonal Antibody, Unconjugated (SL14175R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.

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