Product Name	CYP4B1
Chinese Name	细胞色素P450 4B1抗体
Alias	CP4B1_HUMAN; CYP4B1; CYPIVB1; Cytochrome P450 4B1; Cytochrome P450 family 4 subfamily B polypeptide 1; Cytochrome P450 subfamily IVB polypeptide 1; Cytochrome P450-HP; Microsomal monooxygenase; P450HP.
Research Area	Tumour  Cardiovascular  Cell biology  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	59kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CYP4B1: 51-150/511
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Subcellular Location: Endoplasmic reticulum membrane. Microsome membrane. Tissue Specificity: Detected in the liver and lung (at protein level). Similarity: Belongs to the cytochrome P450 family. SWISS: P13584 Gene ID: 1580 Database links: Entrez Gene: 1580 Human Omim: 124075 Human SwissProt: P13584 Human Unigene: 436317 Human

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