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Product Name CYP2A7 Chinese Name 细胞色素P450 2A7抗体 Alias CP2A7_HUMAN; CPA7; CPAD; CYP2A 7; CYP2A; CYP2A7; CYPIIA7; Cytochrome P450 2A7; Cytochrome P450 family 2 subfamily A polypeptide 7; Cytochrome P450 IIA4; Cytochrome P450 subfamily IIA (phenobarbital inducible) polypeptide 7; Cytochrome P450IIA4; P450 IIA4. Research Area Cell biology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 56kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CYP2A7: 101-200/494 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]
Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular Location:
Endoplasmic reticulum membrane. Microsome membrane.
Similarity:
Belongs to the cytochrome P450 family.
SWISS:
P20853
Gene ID:
1549
Database links:Entrez Gene: 1549 Human
Omim: 608054 Human
SwissProt: P20853 Human
Unigene: 719890 Human
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