Product Name	CHIC2
Chinese Name	CHIC2蛋白抗体
Alias	BrX-like translocated in leukemia; BTL; Chic2; CHIC2_HUMAN; Cystein-rich hydrophobic domain 2; Cysteine-rich hydrophobic domain 2 protein; MGC21173.
Research Area	Tumour  Cell biology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	19kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CHIC2: 61-165/165
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008] Subcellular Location: Cell membrane. Cytoplasmic vesicle. Also present at a Golgi-like vesicular compartment and at scattered vesicles. Post-translational modifications: Palmitoylation in the CHIC motif is required for membrane association. DISEASE: Note=A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6. Similarity: Belongs to the CHIC family. SWISS: Q9UKJ5 Gene ID: 26511 Database links: Entrez Gene: 26511 Human Entrez Gene: 74277 Mouse SwissProt: Q9UKJ5 Human SwissProt: Q9D9G3 Mouse Unigene: 335393 Human Unigene: 239814 Mouse

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