Product Name	CHD6
Chinese Name	ATP依赖的解旋酶CHD6抗体
Alias	ATP dependent helicase CHD6; ATP-dependent helicase CHD6; CHD-6; CHD5; CHD6; CHD6_HUMAN; chromodomain helicase DNA binding protein 6; Chromodomain-helicase-DNA-binding protein 6; KIAA1335; Radiation induced gene B protein; Radiation-induced gene B protein; RIGB; RP4-620E11.2.
Research Area	Cell biology  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	305kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CHD6: 301-400/2715
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	CHD6 is a 2,715 amino acid protein encoded by the human gene CHD6. CHD6 belongs to the Snf2/Rad54 helicase family and contains two chromodomains, one ATP-binding helicase domain and one C-terminal helicase domain. The CHD family of proteins are ATP-dependent chromatin remodeling enzymes which combine chromodomains with SWI2/Snf2 ATPase/helicase motifs and DNA-binding capability. Chromodomains are protein regions of about 40-50 amino acid residues found in proteins associated with chromatin remodeling and manipulation. The domain is highly conserved among both plants and animals and is found in a large variety of proteins from many genomes. Function: Probable transcription regulator. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR Similarity: Belongs to the SNF2/RAD54 helicase family. Contains 2 chromo domains. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. SWISS: Q8TD26 Gene ID: 84181 Database links: Entrez Gene: 84181 Human SwissProt: Q8TD26 Human Unigene: 371979 Human Unigene: 644112 Human

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