Product Name	CHCHD10
Chinese Name	卷曲螺旋结构域蛋白CHCHD10抗体
Alias	C22orf16; CHC10_HUMAN; CHCHD10; Chromosome 22 open reading frame 16; Coiled coil helix coiled coil helix domain containing 10; Coiled coil helix coiled coil helix domain containing protein 10 mitochondrial; Coiled-coil-helix-coiled-coil-helix domain-containing protein 10; MGC70831; mitochondrial; N27C7-4; OTTHUMP00000198408; OTTHUMP00000198409; Protein N27C7-4.
Research Area	Tumour  Cell biology  Neurobiology  Signal transduction  The new supersedes the old  Mitochondrion
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	12.5kDa
Cellular localization	cytoplasmic Mitochondrion
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CHCHD10: 81-142/142
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translo-acations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein, Bcr-Abl, a potent cell proliferation activator found in several types of leukemia. The C22orf16 gene product has been provisionally designated CHCHD10 pending further characterization. Subcellular Location: Mitochondrion. Similarity: Contains 1 CHCH domain. SWISS: Q8WYQ3 Gene ID: 400916 Database links: Entrez Gene: 400916 Human SwissProt: Q8WYQ3 Human Unigene: 66915 Human

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