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Rabbit Anti-CFHL4 antibody
Rabbit Anti-CFHL4 antibody
CFHL4; CFHR4; Complement factor H related 4; Complement factor H-related protein 4; FHR-4; FHR4; FHR4_HUMAN.
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  • NO.:SL13875R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name CFHL4
Chinese Name 补体因子H相关蛋白4抗体
Alias CFHL4; CFHR4; Complement factor H related 4; Complement factor H-related protein 4; FHR-4; FHR4; FHR4_HUMAN.  
Research Area Cardiovascular  Cell biology  The new supersedes the old  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 35kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CFHL4: 231-331/331 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene. [provided by RefSeq, Jan 2011]

Function:
Involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by the liver and secreted in plasma.

Post-translational modifications:
Glycosylated.

Similarity:
Contains 5 Sushi (CCP/SCR) domains.

SWISS:
Q92496

Gene ID:
10877

Database links:

Entrez Gene: 10877 Human

Omim: 605337 Human

SwissProt: Q92496 Human

Unigene: 710100 Human



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