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Product Name Cecropin B Chinese Name 杀菌肽B/天蚕抗菌肽B抗体 Alias CECB1; CECB2; CECB_BOMMO; Lepidopteran A/B. Research Area Cell biology immunology Botany Insect Immunogen Species Rabbit Clonality Polyclonal Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 4.1kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from Silk worm Cecropin B: 27-61/63 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Cecropins are produced by insects, particularly under conditions of infection. Cecropins are bioactive peptides that exhibit activities by interacting with membranes and forming transmembrane channels that allow the free flow of electrolytes, metabolites and water across the phospholipid bilayers. Cecropins A, B and D are close homologues consisting of 35-39 residues. They are found in the pupae of the cecropin moth, but related homologues named lepodopteran, bactericidin, moricin and sarcotoxin are produced by other insects.
Function:
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
Subcellular Location:
Secreted
Tissue Specificity:
Highest expression in fat body and hemocytes. Is also expressed in Malpighian tubules and to a much lesser extent in midgut. Not present in silk gland.
Post-translational modifications:
Lepidopteran-B differs from lepidopteran-A by its hydroxylated residue.
Similarity:
Belongs to the cecropin family.
SWISS:
P04142
Gene ID:
693028
Database links:Entrez Gene: 693028 Silk worm
GenBank: DQ233467 Silk worm
GenBank: S60579 Silk worm
GenBank: S74297 Silk worm
SwissProt: P04142 Silk worm
Unigene: Bmo.151 Silk worm
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