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Product Name phospho-CEBPE (Thr74) Chinese Name 磷酸化transcriptional regulatory factorC/EBPε抗体 Alias CEBPE (phospho T74); p-CEBPE (phospho T74); C/EBP epsilon; CCAAT/enhancer binding protein (C/EBP) epsilon; CCAAT/enhancer binding protein epsilon; CCAAT/enhancer-binding protein epsilon; CEBPE; CEBPE_HUMAN; CRP 1; CRP1. Product Type Phosphorylated anti Research Area Cell biology immunology Signal transduction Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 31kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthesised phosphopeptide derived from human CEBPE around the phosphorylation site of Thr74.: PG(p-T)P Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
Function:
C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.
Subcellular Location:
Nucleus.
Tissue Specificity:
Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines.
Post-translational modifications:
Phosphorylated.
SWISS:
Q15744
Gene ID:
1053
Database links:Entrez Gene: 1053 Human
Entrez Gene: 110794 Mouse
Omim: 600749 Human
SwissProt: Q15744 Human
SwissProt: Q6PZD9 Mouse
Unigene: 558308 Human
Unigene: 236223 Mouse
Unigene: 44462 Rat
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