Product Name	PL6
Chinese Name	胎盘蛋白6抗体
Alias	TMEM115; transmembrane protein 115; PP6; Placental protein 6; TM115_HUMAN.
Research Area	Cell biology  Signal transduction  Epigenetics  Transmembrane protein  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	38kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PL6: 201-300/351
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Transmembrane proteins contain transmembrane domains that are usually characterized by alpha-helical structures. Transmembrane proteins exist as thermodynamically stable hetero- and homodimers that interact with the lipid bilayer and are involved in both material exchange and communication between the cell and the environment. PL6 is a 351 amino acid multi-pass membrane protein that is highly expressed in kidney and skeletal muscle with lower levels of expression detected in liver, placenta, prancreas, lung, heart and brain. PL6 contains one phosphoserine residue and several transmembrane domains, suggesting that it may participate in protein exchange and signaling events between cells. Function: PL6 is an integral membrane protein with signal transduction activity. Subcellular Location: Membrane; Multi-pass membrane protein SWISS: Q12893 Gene ID: 11070 Database links: Entrez Gene: 11070 Human Entrez Gene: 532459 Cow Entrez Gene: 56395 Mouse NCBI: 5902022 Human SwissProt: A4FUB8 Cow SwissProt: Q12893 Human SwissProt: Q9WUH1 Mouse

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