Product Name	NCKAP5
Chinese Name	NCKAP5蛋白抗体
Alias	ERIH1; ERIH2; NAP-5; NAP5; Nck-associated protein 5; NCKAP5; NCKP5_HUMAN; Peripheral clock protein.
Research Area	Signal transduction  Transmembrane protein  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	208kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NCKAP5: 1-100/1909
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	NAP5 (Nck-associated protein 5), also known as peripheral clock protein, NCKAP5 or ERIH, is a 1,909 amino acid nuclear protein that is expressed in fetal and adult brain, leukocytes and fetal fibroblasts. Containing pro-rich sequences, NAP5 interacts with the adapter protein Nck via the SH3-containing region. Existing as four alternatively spliced isoforms, the gene encoding NAP5 maps to human chromosome 2q21.2 and mouse chromosome 1 E3. Human chromosome 2, the second largest human chromosome, consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene present on chromosome 2. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is due to mutations in the ALMS1 gene. Subunit: Interacts with the SH3-containing region of the adapter protein NCK. Tissue Specificity: Expressed in fetal and adult brain, leukocytes and fetal fibroblasts. SWISS: O14513 Gene ID: 344148 Database links: Entrez Gene: 344148 Human SwissProt: O14513 Human Unigene: 537329 Human

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